Haza - Termékek - Inhibitorok és agonisták - Mások - Részletek

NSC 140873(NSC-140873, NSC140873) CAS No.: 106410-13-3

Chemical Structure : NSC 140873
CAS No.: 106410-13-3

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Leírás

Chemical Structure : NSC 140873

CAS No.: 106410-13-3

NSC 140873(NSC-140873, NSC140873)

: URK-V2475

NSC140873 targets is the protein kinase CK2.

NSC140873 targets is the protein kinase CK2.
In addition to its activity against CK2, NSC140873 has also been shown to have anti-tumor activity against a variety of other cancer cell types, including breast, lung, and colon cancer. This broad-spectrum activity makes it a promising candidate for the development of new cancer therapies.

	277.71
	C₁₃H₁₂₃O₂
	106410-13-3

	-20 degree 3years; 4 degree 2years	-80 degree 6 Months -20 degree 1 Months

1. Buontempo F, et al. NSC 140912, a novel inhibitor of CK2, suppresses survival and proliferation of cancer cells. Int J Oncol. 2013 Mar;42(3):791-8.

2. Krennhrubec K, et al. The RNA splicing factor ASF/SF2 inhibits human papillomavirus type 16 E6 splicing and induces apoptosis in cancer cells. Oncotarget. 2016 May 10;7(19):28127-41.

3. Guerra B, et al. NSC 140473, a small molecule CK2 inhibitor, induces apoptosis and inhibits tumor growth in vivo. Cancer Res. 2008 Aug 1;68(15):7487-95.